PTPN3
Gene Ontology Biological Process
- negative regulation of membrane protein ectodomain proteolysis [IMP]
- negative regulation of mitotic cell cycle [IDA]
- peptidyl-tyrosine dephosphorylation [IDA, TAS]
- protein dephosphorylation [IDA]
- regulation of membrane depolarization during action potential [IDA]
- regulation of sodium ion transmembrane transporter activity [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CACYBP
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.
Protein tyrosine phosphorylation, which plays a vital role in a variety of human cellular processes, is coordinated by protein tyrosine kinases and protein tyrosine phosphatases (PTPs). Genomic studies provide compelling evidence that PTPs are frequently mutated in various human cancers, suggesting that they have important roles in tumor suppression. However, the cellular functions and regulatory machineries of most PTPs are ... [more]
Throughput
- High Throughput
Additional Notes
- high-confidence candidate interacting protein
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PTPN3 CACYBP | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID