BAIT
SSH1
SSH1L
slingshot protein phosphatase 1
GO Process (8)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- actin cytoskeleton organization [IMP]
- cell morphogenesis [IMP]
- cellular response to ATP [IDA]
- protein dephosphorylation [IMP]
- regulation of actin polymerization or depolymerization [IBA]
- regulation of axonogenesis [IBA]
- regulation of cellular protein metabolic process [IDA]
- regulation of lamellipodium assembly [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CORO1C
HCRNN4
coronin, actin binding protein, 1C
GO Process (3)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.
Protein tyrosine phosphorylation, which plays a vital role in a variety of human cellular processes, is coordinated by protein tyrosine kinases and protein tyrosine phosphatases (PTPs). Genomic studies provide compelling evidence that PTPs are frequently mutated in various human cancers, suggesting that they have important roles in tumor suppression. However, the cellular functions and regulatory machineries of most PTPs are ... [more]
Mol. Cell Proteomics Sep. 01, 2016; 15(9);3030-44 [Pubmed: 27432908]
Throughput
- High Throughput
Additional Notes
- high-confidence candidate interacting protein
Curated By
- BioGRID