BAIT
UBC
2700054O04Rik, AI194771, Rps27a, TI-225, Uba52, Ubb
ubiquitin C
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
TNIP1
ABIN, ABIN-1, ABIN1, AU018810, Naf1, Nef, VAN
TNFAIP3 interacting protein 1
GO Process (8)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
- MyD88-dependent toll-like receptor signaling pathway [IDA]
- glycoprotein biosynthetic process [ISO]
- leukocyte cell-cell adhesion [ISO]
- modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade [ISO]
- negative regulation of ERK1 and ERK2 cascade [ISO]
- negative regulation of I-kappaB kinase/NF-kappaB signaling [IDA, ISO]
- positive regulation of inflammatory response [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
Gene Ontology Molecular Function
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An Interaction Landscape of Ubiquitin Signaling.
Intracellular signaling via the covalent attachment of different ubiquitin linkages to protein substrates is fundamental to many cellular processes. Although linkage-selective ubiquitin interactors have been studied on a case-by-case basis, proteome-wide analyses have not been conducted yet. Here, we present ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS), a quantitative interaction proteomics method that makes use of chemically synthesized diubiquitin to enrich ... [more]
Mol. Cell Mar. 02, 2017; 65(5);941-955.e8 [Pubmed: 28190767]
Throughput
- High Throughput
Additional Notes
- #LPPI
- Chemically synthesized diubiquitin
- Likely protein-protein interaction
- Mouse embryonic stem cells (ESCs)
- Ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS)
Curated By
- BioGRID