BAIT
UBC
2700054O04Rik, AI194771, Rps27a, TI-225, Uba52, Ubb
ubiquitin C
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
LRP2
AI315343, AW536255, D230004K18Rik, Gp330, Megalin, b2b1625.2Clo, RP23-300E5.2
low density lipoprotein receptor-related protein 2
GO Process (10)
GO Function (7)
GO Component (17)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- apical part of cell [IDA]
- apical plasma membrane [IDA, ISO]
- brush border [IDA, ISO]
- brush border membrane [IDA, ISO]
- coated pit [IDA]
- cytoplasm [ISO]
- endocytic vesicle [IDA]
- endoplasmic reticulum [IDA]
- endosome [IDA, ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- lysosomal membrane [ISO]
- membrane [IDA, ISO]
- membrane raft [ISO]
- protein complex [ISO]
- receptor complex [ISO]
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An Interaction Landscape of Ubiquitin Signaling.
Intracellular signaling via the covalent attachment of different ubiquitin linkages to protein substrates is fundamental to many cellular processes. Although linkage-selective ubiquitin interactors have been studied on a case-by-case basis, proteome-wide analyses have not been conducted yet. Here, we present ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS), a quantitative interaction proteomics method that makes use of chemically synthesized diubiquitin to enrich ... [more]
Mol. Cell Mar. 02, 2017; 65(5);941-955.e8 [Pubmed: 28190767]
Throughput
- High Throughput
Additional Notes
- #LPPI
- Chemically synthesized diubiquitin
- Likely protein-protein interaction
- Mouse embryonic stem cells (ESCs)
- Ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS)
Curated By
- BioGRID