BAIT
UBC
2700054O04Rik, AI194771, Rps27a, TI-225, Uba52, Ubb
ubiquitin C
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RNF168
3110001H15Rik
ring finger protein 168
GO Process (13)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [ISO]
- double-strand break repair [ISO]
- histone H2A K63-linked ubiquitination [ISO]
- histone H2A monoubiquitination [ISO]
- histone H2A-K13 ubiquitination [ISO]
- histone H2A-K15 ubiquitination [ISO]
- isotype switching [IMP]
- negative regulation of transcription elongation from RNA polymerase II promoter [ISO]
- positive regulation of DNA repair [ISO]
- protein K63-linked ubiquitination [ISO]
- protein ubiquitination [ISO]
- response to ionizing radiation [ISO]
- ubiquitin-dependent protein catabolic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An Interaction Landscape of Ubiquitin Signaling.
Intracellular signaling via the covalent attachment of different ubiquitin linkages to protein substrates is fundamental to many cellular processes. Although linkage-selective ubiquitin interactors have been studied on a case-by-case basis, proteome-wide analyses have not been conducted yet. Here, we present ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS), a quantitative interaction proteomics method that makes use of chemically synthesized diubiquitin to enrich ... [more]
Mol. Cell Mar. 02, 2017; 65(5);941-955.e8 [Pubmed: 28190767]
Throughput
- High Throughput
Additional Notes
- #LPPI
- Chemically synthesized diubiquitin
- Likely protein-protein interaction
- Mouse embryonic stem cells (ESCs)
- Ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS)
Curated By
- BioGRID