BAIT
UBC
2700054O04Rik, AI194771, Rps27a, TI-225, Uba52, Ubb
ubiquitin C
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ERCC2
AA407812, AU020867, AW240756, CXPD, Ercc-2, XPD
excision repair cross-complementing rodent repair deficiency, complementation group 2
GO Process (33)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- DNA duplex unwinding [ISO]
- DNA repair [IMP]
- UV protection [IMP, ISO]
- aging [IMP]
- apoptotic process [ISO]
- bone mineralization [IMP]
- cell proliferation [IMP]
- central nervous system myelin formation [IMP]
- chromosome segregation [ISO]
- embryonic cleavage [IMP]
- erythrocyte maturation [IMP]
- extracellular matrix organization [IMP]
- hair cell differentiation [IMP, ISO]
- hair cycle process [IMP]
- hair follicle maturation [IMP]
- hematopoietic stem cell differentiation [IMP]
- in utero embryonic development [IMP]
- multicellular organism growth [IMP]
- nucleotide-excision repair [IMP, ISO]
- nucleotide-excision repair, DNA incision [ISO]
- positive regulation of DNA binding [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- post-embryonic development [IMP]
- protein phosphorylation [ISO]
- regulation of mitotic cell cycle phase transition [ISO]
- response to UV [IMP]
- response to oxidative stress [IMP, ISO]
- skin development [IMP]
- spinal cord development [IMP]
- transcription from RNA polymerase II promoter [ISO]
- transcription-coupled nucleotide-excision repair [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An Interaction Landscape of Ubiquitin Signaling.
Intracellular signaling via the covalent attachment of different ubiquitin linkages to protein substrates is fundamental to many cellular processes. Although linkage-selective ubiquitin interactors have been studied on a case-by-case basis, proteome-wide analyses have not been conducted yet. Here, we present ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS), a quantitative interaction proteomics method that makes use of chemically synthesized diubiquitin to enrich ... [more]
Mol. Cell Mar. 02, 2017; 65(5);941-955.e8 [Pubmed: 28190767]
Throughput
- High Throughput
Additional Notes
- #LPPI
- Chemically synthesized diubiquitin
- Likely protein-protein interaction
- Mouse embryonic stem cells (ESCs)
- Ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS)
Curated By
- BioGRID