BAIT
UBC
2700054O04Rik, AI194771, Rps27a, TI-225, Uba52, Ubb
ubiquitin C
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ERCC1
Ercc-1
excision repair cross-complementing rodent repair deficiency, complementation group 1
GO Process (28)
GO Function (9)
GO Component (6)
Gene Ontology Biological Process
- DNA catabolic process, endonucleolytic [ISO]
- DNA recombination [IMP, ISO]
- DNA repair [IMP]
- UV protection [IMP]
- cell development [IMP]
- cell proliferation [IMP]
- cellular response to DNA damage stimulus [IMP]
- chromosome organization [IMP]
- double-strand break repair [IMP]
- germ cell development [IMP]
- interstrand cross-link repair [IMP]
- isotype switching [IMP]
- male gonad development [IMP]
- mitotic recombination [ISO]
- multicellular organism growth [IGI, IMP]
- multicellular organismal aging [IMP]
- negative regulation of telomere maintenance [ISO]
- nucleotide-excision repair [IMP, ISO]
- nucleotide-excision repair, DNA incision, 3'-to lesion [ISO]
- nucleotide-excision repair, DNA incision, 5'-to lesion [ISO]
- oogenesis [IMP]
- post-embryonic hemopoiesis [IMP]
- pyrimidine dimer repair by nucleotide-excision repair [IMP]
- replicative cell aging [IMP]
- response to X-ray [IMP]
- response to oxidative stress [ISO]
- spermatogenesis [IMP]
- syncytium formation [IMP]
Gene Ontology Molecular Function- TBP-class protein binding [IPI]
- TFIID-class transcription factor binding [IDA]
- damaged DNA binding [ISO]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- single-stranded DNA binding [ISO]
- single-stranded DNA endodeoxyribonuclease activity [ISO]
- structure-specific DNA binding [ISO]
- TBP-class protein binding [IPI]
- TFIID-class transcription factor binding [IDA]
- damaged DNA binding [ISO]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- single-stranded DNA binding [ISO]
- single-stranded DNA endodeoxyribonuclease activity [ISO]
- structure-specific DNA binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An Interaction Landscape of Ubiquitin Signaling.
Intracellular signaling via the covalent attachment of different ubiquitin linkages to protein substrates is fundamental to many cellular processes. Although linkage-selective ubiquitin interactors have been studied on a case-by-case basis, proteome-wide analyses have not been conducted yet. Here, we present ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS), a quantitative interaction proteomics method that makes use of chemically synthesized diubiquitin to enrich ... [more]
Mol. Cell Mar. 02, 2017; 65(5);941-955.e8 [Pubmed: 28190767]
Throughput
- High Throughput
Additional Notes
- #LPPI
- Chemically synthesized diubiquitin
- Likely protein-protein interaction
- Mouse embryonic stem cells (ESCs)
- Ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS)
Curated By
- BioGRID