BAIT
UBC
2700054O04Rik, AI194771, Rps27a, TI-225, Uba52, Ubb
ubiquitin C
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
UBE4B
4930551I19Rik, 4933406G05Rik, AU014668, D4Bwg0973e, UFD2, UFD2a, Ufd2p, mKIAA0684, RP23-173D8.1
ubiquitination factor E4B
GO Process (12)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
- cellular protein catabolic process [IMP]
- granzyme-mediated apoptotic signaling pathway [ISO]
- neuron projection development [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISO]
- protein autoubiquitination [IDA]
- protein monoubiquitination [IDA]
- protein polyubiquitination [IDA, IMP]
- protein ubiquitination [IDA, TAS]
- response to UV [ISO]
- response to endoplasmic reticulum stress [IMP]
- ubiquitin-dependent protein catabolic process [IMP, TAS]
- ventricular trabecula myocardium morphogenesis [IMP]
Gene Ontology Molecular Function
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An Interaction Landscape of Ubiquitin Signaling.
Intracellular signaling via the covalent attachment of different ubiquitin linkages to protein substrates is fundamental to many cellular processes. Although linkage-selective ubiquitin interactors have been studied on a case-by-case basis, proteome-wide analyses have not been conducted yet. Here, we present ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS), a quantitative interaction proteomics method that makes use of chemically synthesized diubiquitin to enrich ... [more]
Mol. Cell Mar. 02, 2017; 65(5);941-955.e8 [Pubmed: 28190767]
Throughput
- High Throughput
Additional Notes
- #LPPI
- Chemically synthesized diubiquitin
- Likely protein-protein interaction
- Mouse embryonic stem cells (ESCs)
- Ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS)
Curated By
- BioGRID