BAIT
UBC
2700054O04Rik, AI194771, Rps27a, TI-225, Uba52, Ubb
ubiquitin C
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
DNMT1
Cxxc9, Dnmt, Dnmt1o, MCMT, MTase, Met-1, Met1, MommeD2, m.MmuI
DNA methyltransferase (cytosine-5) 1
GO Process (20)
GO Function (15)
GO Component (7)
Gene Ontology Biological Process
- C-5 methylation of cytosine [IDA]
- DNA hypermethylation [ISO]
- DNA methylation [IDA, IMP]
- DNA methylation on cytosine [ISO]
- DNA methylation on cytosine within a CG sequence [ISO]
- S-adenosylhomocysteine metabolic process [ISO]
- S-adenosylmethioninamine metabolic process [ISO]
- S-adenosylmethionine metabolic process [ISO]
- cellular response to amino acid stimulus [IDA]
- cellular response to transforming growth factor beta stimulus [ISO]
- gene silencing [IDA]
- maintenance of DNA methylation [IMP, ISO]
- negative regulation of histone H3-K9 methylation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of gene expression [ISO]
- positive regulation of histone H3-K4 methylation [ISO]
- regulation of cell proliferation [IGI]
- regulation of gene expression [IMP]
- response to antidepressant [ISO]
Gene Ontology Molecular Function- DNA (cytosine-5-)-methyltransferase activity [IDA, ISO]
- DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [ISO]
- DNA binding [IDA, ISO]
- DNA-methyltransferase activity [ISO]
- RNA binding [IDA]
- chromatin binding [IDA]
- double-stranded DNA binding [ISO]
- estrogen receptor binding [ISO]
- histone deacetylase binding [ISO]
- methyl-CpG binding [IDA, ISO]
- methyltransferase activity [IDA]
- protein binding [IPI]
- protein domain specific binding [ISO]
- unmethylated CpG binding [ISO]
- zinc ion binding [IDA]
- DNA (cytosine-5-)-methyltransferase activity [IDA, ISO]
- DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [ISO]
- DNA binding [IDA, ISO]
- DNA-methyltransferase activity [ISO]
- RNA binding [IDA]
- chromatin binding [IDA]
- double-stranded DNA binding [ISO]
- estrogen receptor binding [ISO]
- histone deacetylase binding [ISO]
- methyl-CpG binding [IDA, ISO]
- methyltransferase activity [IDA]
- protein binding [IPI]
- protein domain specific binding [ISO]
- unmethylated CpG binding [ISO]
- zinc ion binding [IDA]
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An Interaction Landscape of Ubiquitin Signaling.
Intracellular signaling via the covalent attachment of different ubiquitin linkages to protein substrates is fundamental to many cellular processes. Although linkage-selective ubiquitin interactors have been studied on a case-by-case basis, proteome-wide analyses have not been conducted yet. Here, we present ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS), a quantitative interaction proteomics method that makes use of chemically synthesized diubiquitin to enrich ... [more]
Mol. Cell Mar. 02, 2017; 65(5);941-955.e8 [Pubmed: 28190767]
Throughput
- High Throughput
Additional Notes
- #LPPI
- Chemically synthesized diubiquitin
- Likely protein-protein interaction
- Mouse embryonic stem cells (ESCs)
- Ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS)
Curated By
- BioGRID