BAIT
UBC
2700054O04Rik, AI194771, Rps27a, TI-225, Uba52, Ubb
ubiquitin C
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ACTN1
3110023F10Rik, Actn1a
actinin, alpha 1
GO Process (4)
GO Function (8)
GO Component (14)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Z disc [IDA]
- cell projection [ISO]
- cortical actin cytoskeleton [ISO]
- cortical cytoskeleton [TAS]
- cytoplasm [ISO]
- dendritic spine [ISO]
- dense core granule membrane [TAS]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- fascia adherens [IDA]
- focal adhesion [ISO, TAS]
- nucleus [ISO]
- secretory granule [NAS]
- stress fiber [IDA, ISO, TAS]
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An Interaction Landscape of Ubiquitin Signaling.
Intracellular signaling via the covalent attachment of different ubiquitin linkages to protein substrates is fundamental to many cellular processes. Although linkage-selective ubiquitin interactors have been studied on a case-by-case basis, proteome-wide analyses have not been conducted yet. Here, we present ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS), a quantitative interaction proteomics method that makes use of chemically synthesized diubiquitin to enrich ... [more]
Mol. Cell Mar. 02, 2017; 65(5);941-955.e8 [Pubmed: 28190767]
Throughput
- High Throughput
Additional Notes
- #LPPI
- Chemically synthesized diubiquitin
- Likely protein-protein interaction
- Mouse embryonic stem cells (ESCs)
- Ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS)
Curated By
- BioGRID