BAIT
UBC
2700054O04Rik, AI194771, Rps27a, TI-225, Uba52, Ubb
ubiquitin C
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
GIPC1
GIPC, Glut1CIP, Rgs19ip1, Semcap1, TIP-2, TaxIP2
GIPC PDZ domain containing family, member 1
GO Process (11)
GO Function (7)
GO Component (14)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [TAS]
- endothelial cell migration [IMP]
- glutamate secretion [IMP]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IDA]
- positive regulation of GTPase activity [TAS]
- positive regulation of cytokinesis [ISO]
- positive regulation of transforming growth factor beta receptor signaling pathway [IDA]
- protein targeting [IMP, IPI]
- regulation of protein stability [IDA]
- regulation of synaptic plasticity [IMP]
- synaptic transmission [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- brush border [ISO]
- cell [IMP]
- cell cortex [ISO]
- cytoplasm [IDA]
- cytoplasmic membrane-bounded vesicle [ISO]
- cytosol [IDA, ISO]
- dendritic shaft [IDA]
- dendritic spine [IDA]
- endocytic vesicle [ISO]
- extracellular vesicular exosome [ISO]
- intracellular [IMP]
- membrane [IDA, ISO]
- synaptic vesicle [IDA]
- vesicle membrane [IDA]
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An Interaction Landscape of Ubiquitin Signaling.
Intracellular signaling via the covalent attachment of different ubiquitin linkages to protein substrates is fundamental to many cellular processes. Although linkage-selective ubiquitin interactors have been studied on a case-by-case basis, proteome-wide analyses have not been conducted yet. Here, we present ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS), a quantitative interaction proteomics method that makes use of chemically synthesized diubiquitin to enrich ... [more]
Mol. Cell Mar. 02, 2017; 65(5);941-955.e8 [Pubmed: 28190767]
Throughput
- High Throughput
Additional Notes
- #LPPI
- Chemically synthesized diubiquitin
- Likely protein-protein interaction
- Mouse embryonic stem cells (ESCs)
- Ubiquitin interactor affinity enrichment-mass spectrometry (UbIA-MS)
Curated By
- BioGRID