BAIT

NYAP2

9430031J16Rik, Jr6, Kiaa1486
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
GO Process (2)
GO Function (1)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus
PREY

ARHGAP26

1810044B20Rik, 2610010G17Rik, 4933432P15Rik, AI853435, mKIAA0621
Rho GTPase activating protein 26
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.

Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T

The phosphoinositide 3-kinase (PI3K) pathway has been extensively studied in neuronal function and morphogenesis. However, the precise molecular mechanisms of PI3K activation and its downstream signalling in neurons remain elusive. Here, we report the identification of the Neuronal tYrosine-phosphorylated Adaptor for the PI 3-kinase (NYAP) family of phosphoproteins, which is composed of NYAP1, NYAP2, and Myosin16/NYAP3. The NYAPs are expressed ... [more]

EMBO J. Sep. 23, 2011; 30(23);4739-54 [Pubmed: 21946561]

Throughput

  • Low Throughput

Curated By

  • BioGRID