BAIT
NYAP2
KIAA1486
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
GO Process (2)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Homo sapiens
PREY
CYFIP1
P140SRA-1, SHYC, SRA-1, SRA1
cytoplasmic FMR1 interacting protein 1
GO Process (6)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.
The phosphoinositide 3-kinase (PI3K) pathway has been extensively studied in neuronal function and morphogenesis. However, the precise molecular mechanisms of PI3K activation and its downstream signalling in neurons remain elusive. Here, we report the identification of the Neuronal tYrosine-phosphorylated Adaptor for the PI 3-kinase (NYAP) family of phosphoproteins, which is composed of NYAP1, NYAP2, and Myosin16/NYAP3. The NYAPs are expressed ... [more]
EMBO J. Sep. 23, 2011; 30(23);4739-54 [Pubmed: 21946561]
Throughput
- Low Throughput
Curated By
- BioGRID