TUP
Gene Ontology Biological Process
- amnioserosa maintenance [IMP]
- axon guidance [IMP]
- chaeta development [IMP]
- chaeta morphogenesis [IMP]
- dendrite guidance [IMP]
- dorsal closure [IMP]
- germ-band shortening [IMP]
- head involution [NAS]
- heart development [IMP]
- lymph gland development [IMP]
- motor neuron axon guidance [IMP]
- muscle cell fate determination [IMP]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA]
- notum cell fate specification [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of gene expression [IMP]
- terminal region determination [IGI]
- torso signaling pathway [IGI]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- protein binding [IPI]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- protein binding [IPI]
LIM3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Phenotypic Enhancement
A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
The transcription factors islet and Lim3 combinatorially regulate ion channel gene expression.
Expression of appropriate ion channels is essential to allow developing neurons to form functional networks. Our previous studies have identified LIM-homeodomain (HD) transcription factors (TFs), expressed by developing neurons, that are specifically able to regulate ion channel gene expression. In this study, we use the technique of DNA adenine methyltransferase identification (DamID) to identify putative gene targets of four such ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| TUP LIM3 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - | |
| TUP LIM3 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |