NOP17L
Gene Ontology Molecular Function
PP1-87B
Gene Ontology Biological Process
- adult locomotory behavior [IMP]
- axon guidance [IMP]
- chromosome condensation [IMP, NAS]
- chromosome segregation [IMP]
- learning or memory [NAS]
- locomotion [NAS]
- mitotic metaphase plate congression [IMP]
- mitotic nuclear division [IMP]
- mitotic sister chromatid segregation [NAS]
- mitotic spindle elongation [IMP]
- nervous system development [IMP]
- olfactory learning [IMP]
- oogenesis [IMP]
- phagocytosis [IMP]
- positive regulation of ERK1 and ERK2 cascade [IGI]
- positive regulation of Ras protein signal transduction [IGI]
- protein dephosphorylation [IMP, ISS, NAS]
- spindle assembly [IMP]
- spindle assembly involved in mitosis [IMP]
- visual learning [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Phenotypic Suppression
A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
Towards a comprehensive analysis of the protein phosphatase 1 interactome in Drosophila.
Protein phosphatase type 1 (PP1) is one of the major classes of serine/threonine protein phosphatases, and has been found in all eukaryotic cells examined to date. Metazoans from Drosophila to humans have multiple genes encoding catalytic subunits of PP1 (PP1c), which are involved in a wide range of biological processes. Different PP1c isoforms have pleiotropic and overlapping functions; this has ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| NOP17L PP1-87B | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | FlyBase | - | |
| NOP17L PP1-87B | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | FlyBase | - | |
| PP1-87B NOP17L | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | FlyBase | - | |
| NOP17L PP1-87B | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |