BAIT

CHRO

CG10712, CHRIZ, CHRIZ/CHRO, Chiz, Chr, Chro(Chriz), Dmel\CG10712, anon-EST:fe2E3, Dmel_CG10712
Chromator
Drosophila melanogaster
PREY

EAST

CG4399, Dmel\CG4399, EG:133E12.4, anon-WO03040301.224, l(1)G0014, l(1)G0500, su(w[sp]), Dmel_CG4399
enhanced adult sensory threshold
Drosophila melanogaster

Phenotypic Suppression

A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

EAST and Chromator control the destruction and remodeling of muscles during Drosophila metamorphosis.

Wasser M, Bte Osman Z, Chia W

Metamorphosis involves the destruction of larval, the formation of adult and the transformation of larval into adult tissues. In this study, we demonstrate the role of the Drosophila nuclear proteins EAST and Chromator in tissue destruction and remodeling. To better understand the function of east, we performed a yeast two-hybrid screen and identified the euchromatin associated protein Chromator as a ... [more]

Dev. Biol. Jul. 15, 2007; 307(2);380-93 [Pubmed: 17540360]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
EAST CHRO
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Low-BioGRID
-

Curated By