BAIT
SO
CG11121, Dmel\CG11121, Drl, Mdu, ami, mda, med, old, somda, Dmel_CG11121
sine oculis
GO Process (12)
GO Function (5)
GO Component (1)
Gene Ontology Biological Process
- Bolwig's organ morphogenesis [IMP]
- circadian rhythm [IGI]
- compound eye development [IMP, NAS]
- compound eye morphogenesis [IMP]
- entrainment of circadian clock [IMP]
- eye-antennal disc morphogenesis [TAS]
- glial cell migration [IMP]
- optic lobe placode formation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- regulation of transcription, DNA-templated [ISS]
- ring gland development [IMP]
- spermatogenesis [IMP]
Gene Ontology Molecular Function
Drosophila melanogaster
PREY
GRO
BEST:GM01575, BEST:LD15161, BcDNA.LD33829, BcDNA:LD33829, CG8384, DGro, Dmel\CG8384, E(spl)-WD, E(spl)[2], E(spl)gro, E(spl)m9/m10, En-spl, Grg/TLE, Groucho, anon-WO0118547.385, dAES1, dAES2, l(3)gro, m10, m9, m9-m10, m9/10, m9/m10, Dmel_CG8384
groucho
GO Process (11)
GO Function (7)
GO Component (2)
Gene Ontology Biological Process
- actin filament organization [IMP]
- dendrite morphogenesis [IMP]
- lateral inhibition [IMP]
- negative regulation of Wnt signaling pathway [NAS]
- negative regulation of canonical Wnt signaling pathway [IDA]
- negative regulation of smoothened signaling pathway [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IPI, TAS]
- negative regulation of transcription, DNA-templated [IDA, IGI, NAS, TAS]
- nervous system development [IMP, NAS]
- regulation of transcription, DNA-templated [IGI, IMP]
- sex determination, primary response to X:A ratio [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleus [NAS, TAS]
- protein complex [IPI]
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Partner specificity is essential for proper function of the SIX-type homeodomain proteins Sine oculis and Optix during fly eye development.
The development of the Drosophila visual system utilizes two members of the highly conserved Six-Homeobox family of transcription factor, Sine oculis and Optix. Although in vitro studies have detected differences in DNA-binding and interactions with some co-factors, questions remain as to what extent the activity for these two transcriptional regulators is redundant or specific in vivo. In this work, we ... [more]
Dev. Biol. Oct. 01, 2005; 286(1);158-68 [Pubmed: 16125693]
Throughput
- Low Throughput