ADF1
Gene Ontology Biological Process
- dendrite morphogenesis [IMP]
- larval locomotory behavior [NAS]
- learning or memory [NAS]
- locomotion [IMP]
- long-term memory [TAS]
- memory [IMP]
- olfactory learning [NAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [TAS]
- regulation of dendrite development [IMP]
- regulation of transcription from RNA polymerase II promoter [NAS]
- synapse assembly [IMP]
Gene Ontology Molecular Function
ADF1
Gene Ontology Biological Process
- dendrite morphogenesis [IMP]
- larval locomotory behavior [NAS]
- learning or memory [NAS]
- locomotion [IMP]
- long-term memory [TAS]
- memory [IMP]
- olfactory learning [NAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [TAS]
- regulation of dendrite development [IMP]
- regulation of transcription from RNA polymerase II promoter [NAS]
- synapse assembly [IMP]
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Widespread evidence of cooperative DNA binding by transcription factors in Drosophila development.
Regulation of eukaryotic gene transcription is often combinatorial in nature, with multiple transcription factors (TFs) regulating common target genes, often through direct or indirect mutual interactions. Many individual examples of cooperative binding by directly interacting TFs have been identified, but it remains unclear how pervasive this mechanism is during animal development. Cooperative TF binding should be manifest in genomic sequences ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ADF1 ADF1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |