BAIT
HSPB2
27kDa, 2810021G24Rik, HSP27, MKBP
heat shock protein 2
GO Process (2)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Mus musculus
PREY
VCL
9430097D22, AA571387, AI462105, AW545629
vinculin
GO Process (10)
GO Function (4)
GO Component (16)
Gene Ontology Biological Process
- adherens junction assembly [ISO]
- apical junction assembly [ISO]
- axon extension [IGI]
- cell adhesion [IDA]
- epithelial cell-cell adhesion [ISO]
- lamellipodium assembly [IDA]
- morphogenesis of an epithelium [ISO]
- platelet aggregation [ISO]
- protein localization to cell surface [ISO]
- regulation of cell migration [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Z disc [ISO]
- actin filament [ISO]
- adherens junction [IDA]
- cell-cell adherens junction [ISO]
- cell-cell junction [IDA]
- costamere [IDA, ISO]
- cytoplasm [IDA]
- extracellular vesicular exosome [ISO]
- fascia adherens [IDA]
- focal adhesion [IDA, ISO]
- intercalated disc [ISO]
- plasma membrane [IDA]
- protein complex [ISO]
- sarcolemma [ISO]
- stress fiber [ISO]
- vesicle [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome.
Small Heat Shock Proteins (sHSPs) are molecular chaperones that transiently interact with other proteins, thereby assisting with quality control of proper protein folding and/or degradation. They are also recruited to protect cells from a variety of stresses in response to extreme heat, heavy metals, and oxidative-reductive stress. Although ten human sHSPs have been identified, their likely diverse biological functions remain ... [more]
PLoS ONE Oct. 16, 2015; 10(10);e0133994 [Pubmed: 26465331]
Throughput
- High Throughput
Curated By
- BioGRID