BAIT
HSPB2
27kDa, 2810021G24Rik, HSP27, MKBP
heat shock protein 2
GO Process (2)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Mus musculus
PREY
RAB7
Rab7a
RAB7, member RAS oncogene family
GO Process (14)
GO Function (5)
GO Component (15)
Gene Ontology Biological Process
- GTP catabolic process [IBA, ISO]
- Rab protein signal transduction [IBA]
- bone resorption [ISO]
- early endosome to late endosome transport [ISO]
- endosome to lysosome transport [IBA, ISO]
- epidermal growth factor catabolic process [ISO]
- intracellular protein transport [TAS]
- phagosome acidification [ISO]
- phagosome-lysosome fusion [IBA, ISO]
- positive regulation of exosomal secretion [ISO]
- protein targeting to lysosome [ISO]
- protein to membrane docking [ISO]
- regulation of autophagic vacuole assembly [ISO]
- retrograde transport, endosome to Golgi [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- alveolar lamellar body [ISO]
- cell [TAS]
- cytoplasm [IDA]
- cytoplasmic vesicle [ISO]
- extracellular vesicular exosome [ISO]
- intracellular [TAS]
- intracellular membrane-bounded organelle [ISO]
- late endosome [IDA, ISO]
- lysosome [IBA, ISO]
- phagocytic vesicle [IBA, ISO]
- pre-autophagosomal structure membrane [IDA]
- retromer complex [ISO]
- terminal bouton [ISO]
- vacuolar membrane [IBA]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome.
Small Heat Shock Proteins (sHSPs) are molecular chaperones that transiently interact with other proteins, thereby assisting with quality control of proper protein folding and/or degradation. They are also recruited to protect cells from a variety of stresses in response to extreme heat, heavy metals, and oxidative-reductive stress. Although ten human sHSPs have been identified, their likely diverse biological functions remain ... [more]
PLoS ONE Oct. 16, 2015; 10(10);e0133994 [Pubmed: 26465331]
Throughput
- High Throughput
Curated By
- BioGRID