BAIT
HSPB2
27kDa, 2810021G24Rik, HSP27, MKBP
heat shock protein 2
GO Process (2)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Mus musculus
PREY
OPA1
1200011N24Rik, AI225888, AI847218, lilr3, mKIAA0567
optic atrophy 1
GO Process (14)
GO Function (3)
GO Component (10)
Gene Ontology Biological Process
- GTP catabolic process [TAS]
- cellular senescence [ISO]
- inner mitochondrial membrane organization [ISO]
- mitochondrial fusion [IDA, ISO]
- mitochondrial genome maintenance [ISO]
- mitochondrion organization [IDA, ISO, NAS]
- negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [ISO]
- negative regulation of intrinsic apoptotic signaling pathway [IMP]
- negative regulation of release of cytochrome c from mitochondria [IMP, ISO]
- neural tube closure [IMP]
- positive regulation of dendrite development [ISO]
- positive regulation of mitochondrial fusion [ISO]
- positive regulation of neuron maturation [ISO]
- visual perception [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome.
Small Heat Shock Proteins (sHSPs) are molecular chaperones that transiently interact with other proteins, thereby assisting with quality control of proper protein folding and/or degradation. They are also recruited to protect cells from a variety of stresses in response to extreme heat, heavy metals, and oxidative-reductive stress. Although ten human sHSPs have been identified, their likely diverse biological functions remain ... [more]
PLoS ONE Oct. 16, 2015; 10(10);e0133994 [Pubmed: 26465331]
Throughput
- High Throughput
Curated By
- BioGRID