BAIT
LRRC47
RP1-286D6.3
leucine rich repeat containing 47
GO Process (0)
GO Function (2)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
LUM
LDC, SLRR2D
lumican
GO Process (8)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- collagen fibril organization [NAS]
- extracellular matrix organization [TAS]
- glycosaminoglycan metabolic process [TAS]
- keratan sulfate biosynthetic process [TAS]
- keratan sulfate catabolic process [TAS]
- keratan sulfate metabolic process [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Cellular organelles provide opportunities to relate biological mechanisms to disease. Here we use affinity proteomics, genetics and cell biology to interrogate cilia: poorly understood organelles, where defects cause genetic diseases. Two hundred and seventeen tagged human ciliary proteins create a final landscape of 1,319 proteins, 4,905 interactions and 52 complexes. Reverse tagging, repetition of purifications and statistical analyses, produce a ... [more]
Nat Commun May. 13, 2016; 7(0);11491 [Pubmed: 27173435]
Throughput
- High Throughput
Curated By
- BioGRID