BAIT
FBXO45
Fbx45
F-box protein 45
GO Process (4)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
RFC4
A1, RFC37
replication factor C (activator 1) 4, 37kDa
GO Process (11)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- DNA repair [TAS]
- DNA replication [TAS]
- DNA strand elongation involved in DNA replication [TAS]
- mitotic cell cycle [TAS]
- nucleotide-excision repair [TAS]
- nucleotide-excision repair, DNA gap filling [TAS]
- telomere maintenance [TAS]
- telomere maintenance via recombination [TAS]
- telomere maintenance via semi-conservative replication [TAS]
- transcription-coupled nucleotide-excision repair [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Cellular organelles provide opportunities to relate biological mechanisms to disease. Here we use affinity proteomics, genetics and cell biology to interrogate cilia: poorly understood organelles, where defects cause genetic diseases. Two hundred and seventeen tagged human ciliary proteins create a final landscape of 1,319 proteins, 4,905 interactions and 52 complexes. Reverse tagging, repetition of purifications and statistical analyses, produce a ... [more]
Nat Commun May. 13, 2016; 7(0);11491 [Pubmed: 27173435]
Throughput
- High Throughput
Curated By
- BioGRID