BAIT
ACSL1
ACS1, FACL1, FACL2, LACS, LACS1, LACS2
acyl-CoA synthetase long-chain family member 1
GO Process (10)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- alpha-linolenic acid metabolic process [TAS]
- cellular lipid metabolic process [TAS]
- linoleic acid metabolic process [TAS]
- lipid biosynthetic process [IDA]
- long-chain fatty acid import [IDA]
- long-chain fatty acid metabolic process [IDA]
- long-chain fatty-acyl-CoA biosynthetic process [TAS]
- small molecule metabolic process [TAS]
- triglyceride biosynthetic process [TAS]
- unsaturated fatty acid metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BDH1
BDH, SDR9C1
3-hydroxybutyrate dehydrogenase, type 1
GO Process (5)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Cellular organelles provide opportunities to relate biological mechanisms to disease. Here we use affinity proteomics, genetics and cell biology to interrogate cilia: poorly understood organelles, where defects cause genetic diseases. Two hundred and seventeen tagged human ciliary proteins create a final landscape of 1,319 proteins, 4,905 interactions and 52 complexes. Reverse tagging, repetition of purifications and statistical analyses, produce a ... [more]
Nat Commun May. 13, 2016; 7(0);11491 [Pubmed: 27173435]
Throughput
- High Throughput
Curated By
- BioGRID