BAIT
KALRN
2210407G14Rik, AV235988, DUET, E530005C20Rik, Gm539, Hapip, TRAD, RP23-363L9.1
kalirin, RhoGEF kinase
GO Process (4)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CIT
C030025P15Rik, CRIK, CRIK-SK, Cit-k
citron
GO Process (14)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [ISO]
- Golgi organization [ISO]
- cytokinesis [IMP, ISO]
- dendrite development [IMP]
- generation of neurons [IDA]
- metaphase/anaphase transition of mitotic cell cycle [IMP]
- mitotic nuclear division [IDA]
- mitotic sister chromatid segregation [IMP]
- negative regulation of dendrite morphogenesis [IDA]
- negative regulation of neuron differentiation [ISO]
- positive regulation of cytokinesis [ISO]
- protein phosphorylation [IDA]
- regulation of actin polymerization or depolymerization [ISO]
- spermatogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.
GTPase-activating proteins (GAPs) and guanine exchange factors (GEFs) play essential roles in regulating the activity of small GTPases. Several GAPs and GEFs have been shown to be present at the postsynaptic density (PSD) within excitatory glutamatergic neurons and regulate the activity of glutamate receptors. However, it is not known how synaptic GAP and GEF proteins are organized within the PSD ... [more]
Sci Rep Jul. 13, 2017; 7(1);5272 [Pubmed: 28706196]
Throughput
- High Throughput
Additional Notes
- Postsynaptic density (PSD) interactions
Curated By
- BioGRID