An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

Wilkinson B, Li J, Coba MP

GTPase-activating proteins (GAPs) and guanine exchange factors (GEFs) play essential roles in regulating the activity of small GTPases. Several GAPs and GEFs have been shown to be present at the postsynaptic density (PSD) within excitatory glutamatergic neurons and regulate the activity of glutamate receptors. However, it is not known how synaptic GAP and GEF proteins are organized within the PSD ... [more]

Sci Rep Jul. 13, 2017; 7(1);5272 [Pubmed: 28706196]

Throughput

High Throughput

Additional Notes

Postsynaptic density (PSD) interactions

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
DLGAP1 KALRN	Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.	Li J (2016)	High	-	BioGRID	-
DLGAP1 KALRN	Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.	Li J (2017)	High	-	BioGRID	2333912

Curated By

BioGRID

Interaction Summary

KALRN

Gene Ontology Biological Process

Gene Ontology Molecular Function

enzyme binding [ISO]

Gene Ontology Cellular Component

DLGAP1