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BAIT

KALRN

2210407G14Rik, AV235988, DUET, E530005C20Rik, Gm539, Hapip, TRAD, RP23-363L9.1

kalirin, RhoGEF kinase

GO Process (4)

GO Function (1)

GO Component (4)

Gene Ontology Biological Process

axonogenesis [ISO]

intracellular signal transduction [ISO]

nervous system development [ISO]

regulation of dendrite development [ISO]

Gene Ontology Molecular Function

enzyme binding [ISO]

Gene Ontology Cellular Component

extracellular vesicular exosome [ISO]

neuron projection [ISO]

neuronal cell body [ISO]

perinuclear region of cytoplasm [ISO]

CRISPR Database VEGA MGI Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Mus musculus

PREY

SESTD1

1500031J16Rik, A930010O20, Solo/Trio8, RP23-15E4.1

SEC14 and spectrin domains 1

GO Process (0)

GO Function (7)

GO Component (1)

Gene Ontology Molecular Function

phosphatidic acid binding [ISO]
phosphatidylinositol-3,4-bisphosphate binding [ISO]
phosphatidylinositol-3,5-bisphosphate binding [ISO]
phosphatidylinositol-3-phosphate binding [ISO]
phosphatidylinositol-4,5-bisphosphate binding [ISO]
phosphatidylinositol-4-phosphate binding [ISO]
phosphatidylinositol-5-phosphate binding [ISO]

Gene Ontology Cellular Component

calcium channel complex [ISO]

CRISPR Database MGI Alliance of Genome Resources VEGA Entrez Gene RefSeq UniprotKB Ensembl

Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

Wilkinson B, Li J, Coba MP

GTPase-activating proteins (GAPs) and guanine exchange factors (GEFs) play essential roles in regulating the activity of small GTPases. Several GAPs and GEFs have been shown to be present at the postsynaptic density (PSD) within excitatory glutamatergic neurons and regulate the activity of glutamate receptors. However, it is not known how synaptic GAP and GEF proteins are organized within the PSD ... [more]

Sci Rep Jul. 13, 2017; 7(1);5272 [Pubmed: 28706196]

Throughput

High Throughput

Additional Notes

Postsynaptic density (PSD) interactions

Curated By

BioGRID