DLGAP1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
KCNJ10
Gene Ontology Biological Process
- L-glutamate import [ISO]
- L-glutamate uptake involved in synaptic transmission [IMP]
- adult walking behavior [IMP]
- central nervous system myelination [IMP]
- membrane hyperpolarization [ISO]
- oligodendrocyte development [IMP]
- potassium ion homeostasis [IMP]
- potassium ion import [IBA, ISO]
- potassium ion transmembrane transport [IDA, IMP, ISO]
- potassium ion transport [IDA]
- protein homotetramerization [ISO]
- regulation of ion transmembrane transport [IMP]
- regulation of long-term neuronal synaptic plasticity [IMP]
- regulation of membrane potential [IMP]
- regulation of resting membrane potential [IMP]
- regulation of sensory perception of pain [ISO]
- visual perception [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Throughput
- High Throughput
Additional Notes
- Developmental stage: Adult
- Postsynaptic density (PSD) scaffold protein Dlgap1 was immunoprecipitated and its interactors were identified via mass spec.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| DLGAP1 KCNJ10 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID