DLGAP1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PRKCB
Gene Ontology Biological Process
- B cell activation [IMP]
- B cell receptor signaling pathway [IMP]
- calcium ion transport [IDA]
- cellular calcium ion homeostasis [IDA]
- cellular response to carbohydrate stimulus [IDA]
- histone H3-T6 phosphorylation [ISO]
- negative regulation of glucose transport [IMP]
- negative regulation of insulin receptor signaling pathway [ISO]
- positive regulation of B cell receptor signaling pathway [IMP]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- positive regulation of NF-kappaB transcription factor activity [IMP]
- positive regulation of angiogenesis [IMP]
- positive regulation of vascular endothelial growth factor receptor signaling pathway [IMP]
- protein phosphorylation [IDA]
- regulation of dopamine secretion [ISO]
- regulation of growth [ISO]
- regulation of transcription from RNA polymerase II promoter [ISO]
- response to drug [ISO]
- response to hypoxia [IDA]
Gene Ontology Molecular Function- androgen receptor binding [ISO]
- calcium channel regulator activity [IDA]
- chromatin binding [ISO]
- histone binding [ISO]
- histone kinase activity (H3-T6 specific) [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- protein binding [IPI]
- protein kinase C activity [IDA, ISO]
- protein kinase C binding [ISO]
- protein serine/threonine kinase activity [IDA]
- androgen receptor binding [ISO]
- calcium channel regulator activity [IDA]
- chromatin binding [ISO]
- histone binding [ISO]
- histone kinase activity (H3-T6 specific) [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- protein binding [IPI]
- protein kinase C activity [IDA, ISO]
- protein kinase C binding [ISO]
- protein serine/threonine kinase activity [IDA]
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Throughput
- High Throughput
Additional Notes
- Developmental stage: Adult
- Developmental stage: p14
- Developmental stage: p7
- Postsynaptic density (PSD) scaffold protein Dlgap1 was immunoprecipitated and its interactors were identified via mass spec.
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
DLGAP1 PRKCB | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID