DLGAP1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
UBE2N
Gene Ontology Biological Process
- DNA double-strand break processing [ISO]
- T cell receptor signaling pathway [ISO, ISS]
- double-strand break repair via homologous recombination [ISO]
- histone ubiquitination [ISO]
- positive regulation of DNA repair [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO, ISS]
- positive regulation of histone modification [ISO]
- positive regulation of ubiquitin-protein transferase activity [ISO]
- postreplication repair [IBA, ISO]
- protein K63-linked ubiquitination [IBA, ISO]
- protein ubiquitination [ISO]
- regulation of histone ubiquitination [ISO]
- ubiquitin-dependent protein catabolic process [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Throughput
- High Throughput
Additional Notes
- Developmental stage: Adult
- Developmental stage: p14
- Developmental stage: p7
- Postsynaptic density (PSD) scaffold protein Dlgap1 was immunoprecipitated and its interactors were identified via mass spec.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| DLGAP1 UBE2N | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID