A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

Conserved and Diverged Functions of the Calcineurin-Activated Prz1 Transcription Factor in Fission Yeast.

Chatfield-Reed K, Vachon L, Kwon EJ, Chua G

Gene regulation in response to intracellular calcium is mediated by the calcineurin-activated transcription factor Prz1 in the fission yeastSchizosaccharomyces pombe Genome-wide studies of theCrz1and CrzA fungal orthologs have uncovered numerous target genes involved in conserved and species-specific cellular processes. In contrast, very few target genes of Prz1 have been published. This article identifies an extensive list of genes using transcriptome ... [more]

Genetics Apr. 01, 2016; 202(4);1365-75 [Pubmed: 26896331]

Throughput

Low Throughput

Ontology Terms

flocculation (APO:0000065)

Additional Notes

loss of gsf2 or cbf12 could abrogate the constitutive flocculation observed in prz1 deletion cells

Curated By

BioGRID

Interaction Summary

PRZ1

Gene Ontology Biological Process

Gene Ontology Molecular Function

14-3-3 protein binding [IPI]RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity [IDA]

Gene Ontology Cellular Component

GSF2