Phenotypic Suppression

A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

Conserved and Diverged Functions of the Calcineurin-Activated Prz1 Transcription Factor in Fission Yeast.

Chatfield-Reed K, Vachon L, Kwon EJ, Chua G

Gene regulation in response to intracellular calcium is mediated by the calcineurin-activated transcription factor Prz1 in the fission yeastSchizosaccharomyces pombe Genome-wide studies of theCrz1and CrzA fungal orthologs have uncovered numerous target genes involved in conserved and species-specific cellular processes. In contrast, very few target genes of Prz1 have been published. This article identifies an extensive list of genes using transcriptome ... [more]

Genetics Apr. 01, 2016; 202(4);1365-75 [Pubmed: 26896331]

Throughput

  • Low Throughput

Ontology Terms

  • flocculation (APO:0000065)

Additional Notes

  • loss of gsf2 or cbf12 could abrogate the constitutive flocculation observed in prz1 deletion cells

Curated By

  • BioGRID