BAIT
CYFIP1
E030028J09Rik, P140SRA-1, P140sra1, Shyc, Sra-1, Sra1, l(7)1Rl, l71Rl, l7Rl1, mKIAA0068, pl-1
cytoplasmic FMR1 interacting protein 1
GO Process (5)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ANKRD17
4933425K22Rik, A130069E23Rik, A930008M01, AA407558, AA516750, AU040470, Foe, Gtar, Mask, mKIAA0697
ankyrin repeat domain 17
GO Process (11)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- blood vessel maturation [IMP]
- defense response to bacterium [ISO]
- endoderm development [TAS]
- innate immune response [ISO]
- negative regulation of smooth muscle cell differentiation [IMP]
- positive regulation of G1/S transition of mitotic cell cycle [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of MDA-5 signaling pathway [ISO]
- positive regulation of RIG-I signaling pathway [ISO]
- positive regulation of cell cycle [ISO]
- regulation of DNA replication [ISO]
Gene Ontology Molecular Function
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult postsynaptic density (PSD)
Curated By
- BioGRID