BAIT
CYFIP1
E030028J09Rik, P140SRA-1, P140sra1, Shyc, Sra-1, Sra1, l(7)1Rl, l71Rl, l7Rl1, mKIAA0068, pl-1
cytoplasmic FMR1 interacting protein 1
GO Process (5)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
DNM1L
6330417M19Rik, AI450666, Dlp1, Dnmlp1, Drp1, python
dynamin 1-like
GO Process (19)
GO Function (5)
GO Component (11)
Gene Ontology Biological Process
- GTP catabolic process [ISO]
- dynamin polymerization involved in mitochondrial fission [ISO]
- membrane fission involved in mitochondrial fission [ISO]
- membrane fusion [ISO]
- mitochondrial fission [IMP, ISO]
- mitochondrial fragmentation involved in apoptotic process [ISO]
- mitochondrion morphogenesis [ISO]
- necroptotic process [IMP, ISO]
- peroxisome fission [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of intrinsic apoptotic signaling pathway [ISO]
- positive regulation of protein secretion [ISO]
- positive regulation of release of cytochrome c from mitochondria [ISO]
- protein homotetramerization [ISO]
- protein localization to mitochondrion [IMP]
- regulation of mitochondrion organization [ISO]
- regulation of peroxisome organization [ISO]
- regulation of protein oligomerization [ISO]
- release of cytochrome c from mitochondria [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult postsynaptic density (PSD)
Curated By
- BioGRID