BAIT
CYFIP1
E030028J09Rik, P140SRA-1, P140sra1, Shyc, Sra-1, Sra1, l(7)1Rl, l71Rl, l7Rl1, mKIAA0068, pl-1
cytoplasmic FMR1 interacting protein 1
GO Process (5)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
DNM2
Dyn2, Udnm, b2b2159Clo
dynamin 2
GO Process (6)
GO Function (4)
GO Component (14)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- cell junction [ISO]
- clathrin-coated endocytic vesicle [ISO]
- coated pit [ISO]
- cytoplasm [ISO]
- cytosol [ISO]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO]
- growth cone [ISO]
- microtubule [ISO]
- nucleus [ISO]
- photoreceptor inner segment [IDA]
- postsynaptic membrane [ISO]
- protein complex [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult postsynaptic density (PSD)
Curated By
- BioGRID