BAIT

CYFIP1

E030028J09Rik, P140SRA-1, P140sra1, Shyc, Sra-1, Sra1, l(7)1Rl, l71Rl, l7Rl1, mKIAA0068, pl-1
cytoplasmic FMR1 interacting protein 1
Mus musculus
PREY

ERC2

6430531D06, CAST, CAST1/ERC2, D14Ertd171e, ELKS2alpha
ELKS/RAB6-interacting/CAST family member 2
GO Process (0)
GO Function (3)
GO Component (8)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

Li J, Zhang W, Yang H, Howrigan DP, Wilkinson B, Souaiaia T, Evgrafov OV, Genovese G, Clementel VA, Tudor JC, Abel T, Knowles JA, Neale BM, Wang K, Sun F, Coba MP

The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]

Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]

Throughput

  • High Throughput

Additional Notes

  • Adult postsynaptic density (PSD)

Curated By

  • BioGRID