BAIT
CYFIP1
E030028J09Rik, P140SRA-1, P140sra1, Shyc, Sra-1, Sra1, l(7)1Rl, l71Rl, l7Rl1, mKIAA0068, pl-1
cytoplasmic FMR1 interacting protein 1
GO Process (5)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
OPA1
1200011N24Rik, AI225888, AI847218, lilr3, mKIAA0567
optic atrophy 1
GO Process (14)
GO Function (3)
GO Component (10)
Gene Ontology Biological Process
- GTP catabolic process [TAS]
- cellular senescence [ISO]
- inner mitochondrial membrane organization [ISO]
- mitochondrial fusion [IDA, ISO]
- mitochondrial genome maintenance [ISO]
- mitochondrion organization [IDA, ISO, NAS]
- negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [ISO]
- negative regulation of intrinsic apoptotic signaling pathway [IMP]
- negative regulation of release of cytochrome c from mitochondria [IMP, ISO]
- neural tube closure [IMP]
- positive regulation of dendrite development [ISO]
- positive regulation of mitochondrial fusion [ISO]
- positive regulation of neuron maturation [ISO]
- visual perception [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult postsynaptic density (PSD)
Curated By
- BioGRID