BAIT
FMR1
FMRP, Fmr-1
fragile X mental retardation syndrome 1
GO Process (2)
GO Function (5)
GO Component (15)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell body [ISO]
- cytoplasm [ISO]
- cytoplasmic ribonucleoprotein granule [ISO]
- cytoplasmic stress granule [IDA]
- dendrite [IDA, ISO]
- dendritic shaft [ISO]
- dendritic spine [ISO]
- mRNA cap binding complex [IDA]
- membrane [ISO]
- microtubule [ISO]
- neuron projection [ISO]
- neuronal ribonucleoprotein granule [IDA, ISO]
- nucleus [IDA]
- polysome [IBA, ISO]
- synapse [ISO]
Mus musculus
PREY
GIGYF2
2610016F01Rik, A830080H02Rik, AI852361, AW259676, BC006835, Tnrc15, mKIAA0642
GRB10 interacting GYF protein 2
GO Process (12)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- adult locomotory behavior [IMP]
- cellular protein metabolic process [IMP]
- feeding behavior [IMP]
- homeostasis of number of cells within a tissue [IMP]
- insulin-like growth factor receptor signaling pathway [IMP]
- mitotic G1 DNA damage checkpoint [IMP]
- multicellular organism growth [IMP]
- musculoskeletal movement [IMP]
- negative regulation of translation [ISO]
- neuromuscular process controlling balance [IMP]
- post-embryonic development [IMP]
- spinal cord motor neuron differentiation [IMP]
Gene Ontology Molecular Function
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult non-postsynaptic density (PSD)
- e14
Curated By
- BioGRID