FXR1
Gene Ontology Biological Process
Gene Ontology Molecular Function
AGO2
Gene Ontology Biological Process
- RNA phosphodiester bond hydrolysis, endonucleolytic [IDA, ISO]
- gene silencing by RNA [IMP]
- mRNA cleavage [IMP]
- mRNA cleavage involved in gene silencing by miRNA [ISO]
- miRNA metabolic process [IDA]
- negative regulation of translation involved in gene silencing by miRNA [ISO]
- negative regulation of translational initiation [ISO]
- positive regulation of gene expression [IMP]
- positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [IMP]
- positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [IMP]
- post-embryonic development [IMP]
- pre-miRNA processing [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Throughput
- High Throughput
Additional Notes
- Adult non-postsynaptic density (PSD)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| FXR1 AGO2 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.706 | BioGRID | 2661997 |
Curated By
- BioGRID