BAIT
FXR1
1110050J02Rik, 9530073J07Rik, AI851072, Fxr1h, Fxr1p
fragile X mental retardation gene 1, autosomal homolog
GO Process (2)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
CCAR2
2610301G19Rik, mKIAA1967
cell cycle activator and apoptosis regulator 2
GO Process (11)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- RNA splicing [ISO]
- mitochondrial fragmentation involved in apoptotic process [ISO]
- negative regulation of catalytic activity [IDA, ISO]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [ISO]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [ISO]
- positive regulation of DNA damage checkpoint [ISO]
- positive regulation of apoptotic process [ISO]
- regulation of DNA-templated transcription, elongation [ISO]
- regulation of circadian rhythm [IMP]
- regulation of protein stability [ISO]
- response to UV [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- e14
Curated By
- BioGRID