BAIT
FXR1
1110050J02Rik, 9530073J07Rik, AI851072, Fxr1h, Fxr1p
fragile X mental retardation gene 1, autosomal homolog
GO Process (2)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
CNOT1
6030411K04Rik, AA815922, D830048B13
CCR4-NOT transcription complex, subunit 1
GO Process (9)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- RNA phosphodiester bond hydrolysis, exonucleolytic [ISO]
- negative regulation of intracellular estrogen receptor signaling pathway [ISO]
- negative regulation of retinoic acid receptor signaling pathway [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of cytoplasmic mRNA processing body assembly [ISO]
- positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [ISO]
- positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [ISO]
- regulation of stem cell maintenance [IMP, ISO]
- trophectodermal cell differentiation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- e14
Curated By
- BioGRID