BAIT
FXR1
1110050J02Rik, 9530073J07Rik, AI851072, Fxr1h, Fxr1p
fragile X mental retardation gene 1, autosomal homolog
GO Process (2)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
SNW1
2310008B08Rik, AW048543, NCoA-62, SKIP, Skiip
SNW domain containing 1
GO Process (16)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
- cellular response to retinoic acid [IDA, ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [ISO]
- mRNA splicing, via spliceosome [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- positive regulation by host of viral transcription [ISO]
- positive regulation of histone H3-K4 methylation [ISO]
- positive regulation of mRNA splicing, via spliceosome [ISO]
- positive regulation of neurogenesis [IDA]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transforming growth factor beta receptor signaling pathway [ISO]
- positive regulation of vitamin D receptor signaling pathway [ISO]
- regulation of retinoic acid receptor signaling pathway [ISO]
- regulation of vitamin D receptor signaling pathway [ISO]
- retinoic acid receptor signaling pathway [ISO]
- skeletal muscle cell differentiation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- e14
Curated By
- BioGRID