BAIT
HCN1
Bcng1, C630013B14Rik, HAC2
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
GO Process (7)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
DSCAM
4932410A21Rik
Down syndrome cell adhesion molecule
GO Process (7)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- dendrite morphogenesis [IMP]
- dendrite self-avoidance [IMP]
- locomotory behavior [IMP]
- negative regulation of cell adhesion [IMP]
- positive regulation of axon extension involved in axon guidance [IDA, ISO]
- positive regulation of phosphorylation [ISO]
- post-embryonic retina morphogenesis in camera-type eye [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult non-postsynaptic density (PSD)
Curated By
- BioGRID