BAIT
MYCBP2
AU023734, AW107953, AW546647, C130061D10Rik, Pam, Phr1, R75243
MYC binding protein 2
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- branchiomotor neuron axon guidance [IMP]
- cell morphogenesis involved in neuron differentiation [IMP]
- central nervous system projection neuron axonogenesis [IMP]
- motor neuron axon guidance [IMP]
- negative regulation of protein catabolic process [IDA]
- regulation of cytoskeleton organization [IMP]
- regulation of protein localization [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
MTOR
2610315D21Rik, AI327068, FRAP, FRAP2, Frap1, RAFT1, RAPT1, flat, RP23-423L9.1
mechanistic target of rapamycin (serine/threonine kinase)
GO Process (41)
GO Function (11)
GO Component (13)
Gene Ontology Biological Process
- TOR signaling [ISO]
- cell growth [ISO]
- cell projection organization [IMP, ISO]
- cellular response to hypoxia [IDA]
- cellular response to nutrient levels [IDA]
- double-strand break repair via homologous recombination [IBA]
- germ cell development [IDA]
- negative regulation of NFAT protein import into nucleus [IMP]
- negative regulation of autophagy [IMP]
- negative regulation of cell size [IGI, ISO]
- negative regulation of macroautophagy [IMP]
- peptidyl-serine phosphorylation [IMP, ISO]
- peptidyl-threonine phosphorylation [IDA]
- phosphorylation [ISO]
- positive regulation of actin filament polymerization [IDA, IMP]
- positive regulation of endothelial cell proliferation [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of lamellipodium assembly [IDA]
- positive regulation of lipid biosynthetic process [ISO]
- positive regulation of myotube differentiation [IGI]
- positive regulation of peptidyl-tyrosine phosphorylation [IMP]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of stress fiber assembly [IDA]
- positive regulation of transcription from RNA polymerase III promoter [ISO]
- positive regulation of translation [ISO]
- protein autophosphorylation [ISO]
- protein phosphorylation [ISO]
- regulation of Rac GTPase activity [IMP]
- regulation of actin cytoskeleton organization [ISO]
- regulation of carbohydrate metabolic process [ISO]
- regulation of carbohydrate utilization [ISO]
- regulation of fatty acid beta-oxidation [ISO]
- regulation of glycogen biosynthetic process [ISO]
- regulation of myelination [IMP]
- regulation of protein kinase activity [IGI]
- regulation of response to food [ISO]
- response to amino acid [IDA, ISO]
- response to insulin [IDA]
- response to stress [ISO]
- ruffle organization [IDA]
Gene Ontology Molecular Function- RNA polymerase III type 1 promoter DNA binding [ISO]
- RNA polymerase III type 2 promoter DNA binding [ISO]
- RNA polymerase III type 3 promoter DNA binding [ISO]
- TFIIIC-class transcription factor binding [ISO]
- kinase activity [ISO]
- phosphoprotein binding [ISO]
- protein binding [IPI]
- protein dimerization activity [IBA]
- protein domain specific binding [ISO]
- protein serine/threonine kinase activity [IDA, ISO]
- ribosome binding [IDA]
- RNA polymerase III type 1 promoter DNA binding [ISO]
- RNA polymerase III type 2 promoter DNA binding [ISO]
- RNA polymerase III type 3 promoter DNA binding [ISO]
- TFIIIC-class transcription factor binding [ISO]
- kinase activity [ISO]
- phosphoprotein binding [ISO]
- protein binding [IPI]
- protein dimerization activity [IBA]
- protein domain specific binding [ISO]
- protein serine/threonine kinase activity [IDA, ISO]
- ribosome binding [IDA]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult non-postsynaptic density (PSD)
Curated By
- BioGRID