BAIT
MYCBP2
AU023734, AW107953, AW546647, C130061D10Rik, Pam, Phr1, R75243
MYC binding protein 2
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- branchiomotor neuron axon guidance [IMP]
- cell morphogenesis involved in neuron differentiation [IMP]
- central nervous system projection neuron axonogenesis [IMP]
- motor neuron axon guidance [IMP]
- negative regulation of protein catabolic process [IDA]
- regulation of cytoskeleton organization [IMP]
- regulation of protein localization [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
PDE1B
Pde1b1
phosphodiesterase 1B, Ca2+-calmodulin dependent
GO Process (11)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
- cAMP catabolic process [ISO]
- cGMP catabolic process [ISO]
- cellular response to granulocyte macrophage colony-stimulating factor stimulus [ISO]
- cellular response to macrophage colony-stimulating factor stimulus [ISO]
- locomotory behavior [IMP]
- regulation of dopamine metabolic process [IMP]
- regulation of neurotransmitter levels [IMP]
- response to amphetamine [IGI, IMP]
- serotonin metabolic process [IMP]
- signal transduction [IMP]
- visual learning [IGI, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult non-postsynaptic density (PSD)
- e14
Curated By
- BioGRID