BAIT
MYCBP2
AU023734, AW107953, AW546647, C130061D10Rik, Pam, Phr1, R75243
MYC binding protein 2
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- branchiomotor neuron axon guidance [IMP]
- cell morphogenesis involved in neuron differentiation [IMP]
- central nervous system projection neuron axonogenesis [IMP]
- motor neuron axon guidance [IMP]
- negative regulation of protein catabolic process [IDA]
- regulation of cytoskeleton organization [IMP]
- regulation of protein localization [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
PKN1
DBK, F730027O18Rik, PAK1, PRK1, Pkn, Prkcl1, Stk3
protein kinase N1
GO Process (15)
GO Function (12)
GO Component (7)
Gene Ontology Biological Process
- B cell apoptotic process [IMP]
- B cell homeostasis [IMP]
- epithelial cell migration [ISO]
- histone H3-T11 phosphorylation [ISO]
- hyperosmotic response [IDA]
- negative regulation of B cell proliferation [IMP]
- negative regulation of protein kinase activity [IMP]
- negative regulation of protein phosphorylation [IMP]
- protein phosphorylation [IMP, ISO]
- regulation of cell motility [ISO]
- regulation of germinal center formation [IMP]
- regulation of immunoglobulin production [IMP]
- regulation of transcription from RNA polymerase II promoter [ISO]
- renal system process [IMP]
- spleen development [IMP]
Gene Ontology Molecular Function- GTP-Rho binding [ISO]
- Rac GTPase binding [ISO]
- androgen receptor binding [ISO]
- chromatin binding [ISO]
- histone binding [ISO]
- histone deacetylase binding [ISO]
- histone kinase activity (H3-T11 specific) [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- protein binding [IPI]
- protein kinase C binding [ISO]
- protein kinase activity [IMP, ISO]
- protein serine/threonine kinase activity [ISO]
- GTP-Rho binding [ISO]
- Rac GTPase binding [ISO]
- androgen receptor binding [ISO]
- chromatin binding [ISO]
- histone binding [ISO]
- histone deacetylase binding [ISO]
- histone kinase activity (H3-T11 specific) [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- protein binding [IPI]
- protein kinase C binding [ISO]
- protein kinase activity [IMP, ISO]
- protein serine/threonine kinase activity [ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult non-postsynaptic density (PSD)
- e14
Curated By
- BioGRID