BAIT
MYCBP2
AU023734, AW107953, AW546647, C130061D10Rik, Pam, Phr1, R75243
MYC binding protein 2
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- branchiomotor neuron axon guidance [IMP]
- cell morphogenesis involved in neuron differentiation [IMP]
- central nervous system projection neuron axonogenesis [IMP]
- motor neuron axon guidance [IMP]
- negative regulation of protein catabolic process [IDA]
- regulation of cytoskeleton organization [IMP]
- regulation of protein localization [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
TPR
2610029M07Rik, C77892
translocated promoter region, nuclear basket protein
GO Process (18)
GO Function (10)
GO Component (11)
Gene Ontology Biological Process
- MAPK import into nucleus [ISO]
- RNA export from nucleus [ISO]
- RNA import into nucleus [ISO]
- cellular response to heat [ISO]
- cellular response to interferon-alpha [IDA]
- mRNA export from nucleus in response to heat stress [ISO]
- mitotic spindle assembly checkpoint [ISO]
- negative regulation of RNA export from nucleus [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of translational initiation [ISO]
- positive regulation of heterochromatin assembly [ISO]
- positive regulation of intracellular protein transport [ISO]
- positive regulation of mitotic cell cycle spindle assembly checkpoint [ISO]
- positive regulation of protein export from nucleus [ISO]
- positive regulation of protein import into nucleus [ISO]
- regulation of mitotic sister chromatid separation [ISO]
- regulation of spindle assembly involved in mitosis [ISO]
- response to epidermal growth factor [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- e14
Curated By
- BioGRID