BAIT
MYCBP2
AU023734, AW107953, AW546647, C130061D10Rik, Pam, Phr1, R75243
MYC binding protein 2
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- branchiomotor neuron axon guidance [IMP]
- cell morphogenesis involved in neuron differentiation [IMP]
- central nervous system projection neuron axonogenesis [IMP]
- motor neuron axon guidance [IMP]
- negative regulation of protein catabolic process [IDA]
- regulation of cytoskeleton organization [IMP]
- regulation of protein localization [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
UACA
2700059D02Rik, nucling
uveal autoantigen with coiled-coil domains and ankyrin repeats
GO Process (8)
GO Function (1)
GO Component (11)
Gene Ontology Biological Process
- intrinsic apoptotic signaling pathway in response to DNA damage [IMP]
- intrinsic apoptotic signaling pathway in response to oxidative stress [IMP]
- negative regulation of NF-kappaB import into nucleus [IMP]
- negative regulation of inflammatory response [IMP]
- positive regulation of apoptotic process [IDA, IMP]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA, IMP]
- positive regulation of protein import into nucleus [IMP]
- response to UV [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- e14
Curated By
- BioGRID