BAIT
PDE4DIP
4732458A06Rik, 9430063L05Rik, C87016, D130016K21Rik, D3Bwg1078e, Usmg4, mKIAA0454
phosphodiesterase 4D interacting protein (myomegalin)
GO Process (1)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
BCR
5133400C09Rik, AI561783, AI853148, mKIAA3017
breakpoint cluster region
GO Process (14)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- actin cytoskeleton organization [IGI]
- brain development [IGI]
- inner ear morphogenesis [IGI]
- negative regulation of cell migration [IGI]
- negative regulation of inflammatory response [IMP]
- negative regulation of neutrophil degranulation [IGI]
- neuromuscular process controlling balance [IGI]
- platelet-derived growth factor receptor signaling pathway [ISO]
- positive regulation of GTPase activity [IDA]
- positive regulation of Rac GTPase activity [IGI]
- positive regulation of phagocytosis [IGI]
- protein autophosphorylation [ISO]
- regulation of cell cycle [IDA]
- response to lipopolysaccharide [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult non-postsynaptic density (PSD)
Curated By
- BioGRID