BAIT
PDE4DIP
4732458A06Rik, 9430063L05Rik, C87016, D130016K21Rik, D3Bwg1078e, Usmg4, mKIAA0454
phosphodiesterase 4D interacting protein (myomegalin)
GO Process (1)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
PURA
CAGER-1, Pur-alpha, ssCRE-BP
purine rich element binding protein A
GO Process (9)
GO Function (11)
GO Component (5)
Gene Ontology Biological Process
- DNA unwinding involved in DNA replication [ISO]
- apoptotic process [NAS]
- cell differentiation [NAS]
- cell proliferation [NAS]
- mitotic cell cycle checkpoint [NAS]
- negative regulation of transcription, DNA-templated [IDA]
- negative regulation of translation [IDA]
- nervous system development [IMP]
- positive regulation of cell proliferation [IMP]
Gene Ontology Molecular Function- DNA binding [IDA]
- SMAD binding [IDA]
- double-stranded DNA binding [IDA]
- double-stranded telomeric DNA binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- purine-rich negative regulatory element binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [IDA]
- transcription factor binding [IPI]
- translation repressor activity, nucleic acid binding [IDA]
- DNA binding [IDA]
- SMAD binding [IDA]
- double-stranded DNA binding [IDA]
- double-stranded telomeric DNA binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- purine-rich negative regulatory element binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [IDA]
- transcription factor binding [IPI]
- translation repressor activity, nucleic acid binding [IDA]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult non-postsynaptic density (PSD)
Curated By
- BioGRID